The Cleveland Leadership Center offers a number of programs to develop area leaders and encourage greater civic engagement among Cleveland professionals. Leadership Cleveland is a nine-month program for 65 selected community leaders from all sectors to learn about the issues facing Cleveland and develop potential solutions to area challenges through once-monthly sessions and program events.

Leadership Cincinnati USA is a ten-month program offered by the Cincinnati USA Regional Chamber to prepare participants for more active involvement in public affairs. Approximately 48 people are chosen annually to participate in eight day-long sessions, two overnight conferences, and a graduation program. Program sessions and conferences educate participants on issues most important to the Greater Cincinnati community whilte encouraging civic responsibility, engagement, and leadership upon concluding the program.

Leadership Akron is a leadership development class that meets once-monthly to educate class members about vital aspects of the greater Akron community. Each year, 34 participants are selected to analyze major areas of community concern, provides opportunities for open dialogue between leaders with diverse perspectives, examines leadership styles, and promotes a network of community trustees committed to the greater good.